Does Xara Designer support pressure sensitive tablets?

Yes, if you have a pressure sensitive input device (such as a graphics tablet or pen), you can give the line design variable sizing and a brush either variable transparency, variable sizing or both.

To enable pressure sensitive drawing (you must of course have a pressure sensitive tablet and pen) select the  icon on the Freehand tool Infobar.

Note all versions prior to version 6 do not support pressure sensitivity on a normal line.